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Bus from Columbia, SC to San Diego, CA
More travel options
You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.
Enjoy free onboard Wi-Fi
We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.
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Reserve your favorite seat when you book your ticket.
Need to make a change?
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Bus stations and stops in Columbia, SC
Discover more popular bus connections
- Columbia, SC - Atlanta, GA
- Charlotte, NC - Columbia, SC
- Atlanta, GA - Columbia, SC
- Columbia, SC - Charlotte, NC
- North Charleston, SC - Columbia, SC
- Columbia, SC - North Charleston, SC
- Myrtle Beach, SC - Columbia, SC
- Columbia, SC - Myrtle Beach, SC
- Savannah, GA - Columbia, SC
- Florence, SC - Columbia, SC
- Columbia, SC - New York, NY
- Raleigh, NC - Columbia, SC
- Columbia, SC - Washington, D.C.
- Columbia, SC - Savannah, GA
- Orangeburg, SC - Columbia, SC
- Columbia, SC - Florence, SC
- Greensboro, NC - Columbia, SC
- Fayetteville, NC - Columbia, SC
- Columbia, SC - Fayetteville, NC
- Birmingham, AL - Columbia, SC
- Los Angeles, CA - San Diego, CA
- San Diego, CA - Los Angeles, CA
- San Diego, CA - Orange County-Anaheim-Santa Ana, CA
- Phoenix-Tempe, AZ - San Diego, CA
- Orange County-Anaheim-Santa Ana, CA - San Diego, CA
- San Diego, CA - Phoenix-Tempe, AZ
- San Diego, CA - Las Vegas, NV
- Las Vegas, NV - San Diego, CA
- Long Beach, CA - San Diego, CA
- San Diego, CA - Long Beach, CA
- San Diego, CA - Calexico, CA
- Riverside, CA - San Diego, CA
- San Diego, CA - Riverside, CA
- Calexico, CA - San Diego, CA
- San Francisco, CA - San Diego, CA
- San Diego, CA - San Francisco, CA
- San Jose, CA - San Diego, CA
- San Bernardino, CA - San Diego, CA
- San Diego, CA - Sacramento, CA
- San Diego, CA - San Jose, CA
Onboard services are subject to availability