Bus from San Luis Obispo, CA to San Francisco, CA
More travel options
You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.
Enjoy free onboard Wi-Fi
We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.
Reserve a Seat
Reserve your favorite seat when you book your ticket.
Need to make a change?
Easily change your ticket or add bags with Manage My Booking.
What to expect of your trip
Fast, easy, and affordable options from San Luis Obispo, CA to San Francisco, CA
Avg. trip duration
4hr27mins
Avg. distance
234 miles
Cheapest trip
From $69.98
1
Avg. trips a day
On this page
Bus stations and stops in San Luis Obispo, CA
San Luis Obispo Railroad Museum
1940 Santa Barbara Ave
San Luis Obispo, CA 93401
United States
San Luis Obispo, CA 93401
United States
View this address on Google Maps
Bus will board at the bus slips located south of the San Luis Obispo Railroad Museum near High St.
To view more info about this station, visit our page San Luis Obispo Railroad Museum
San Luis Obispo (Cal Poly SLO)
1 Grand Ave
San Luis Obispo, CA 93405
United States
San Luis Obispo, CA 93405
United States
View this address on Google Maps
To view more info about this station, visit our page San Luis Obispo (Cal Poly SLO)
San Luis Obispo Train Station
1011 Railroad Ave
San Luis Obispo, CA 93401
United States
San Luis Obispo, CA 93401
United States
View this address on Google Maps
To view more info about this station, visit our page San Luis Obispo Train Station
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Frequently asked questions
Where are the Greyhound bus stops in San Luis Obispo and in San Francisco?
How long does the bus from San Luis Obispo to San Francisco take with Greyhound?
How much is the bus from San Luis Obispo to San Francisco and how can I buy a ticket?
How do I track my Greyhound bus from San Luis Obispo to San Francisco ?
How much baggage can I bring on the bus from San Luis Obispo to San Francisco?
Is traveling with Greyhound from San Luis Obispo to San Francisco environmentally-friendly?
What onboard services are available on Greyhound buses from San Luis Obispo to San Francisco?
What time is the first bus from San Luis Obispo to San Francisco?
What time is the last bus from San Luis Obispo to San Francisco?
Can I book bus tickets both for Greyhound and FlixBus to travel from San Luis Obispo to San Francisco?
How many daily Greyhound bus trips are there from San Luis Obispo to San Francisco?
What facilities does Greyhound provide for passengers with reduced mobility and service animals?
Plan your bus trip from San Luis Obispo to San Francisco with Greyhound
The trip from San Luis Obispo to San Francisco takes as short as 4 hours 35 minutes and could cost as little as $69.98. The first bus departs at 1:30 pm. Greyhound offers daily bus rides from San Luis Obispo to San Francisco. When traveling with Greyhound to San Francisco from San Luis Obispo, expect free Wifi, power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to San Francisco in seconds.How to Book Your Bus Ticket to San Francisco from San Luis Obispo
With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from San Luis Obispo to San Francisco, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to San Francisco, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!Discover more popular bus connections
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Onboard services are subject to availability