Bus from San Francisco, CA to San Diego, CA
More travel options
You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.
Enjoy free onboard Wi-Fi
We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.
Reserve a Seat
Reserve your favorite seat when you book your ticket.
Need to make a change?
Easily change your ticket or add bags with Manage My Booking.
What to expect of your trip
Fast, easy, and affordable options from San Francisco, CA to San Diego, CA
Avg. trip duration
13hr5mins
Avg. distance
529 miles
Cheapest trip
From $70.97
1
Avg. trips a day
On this page
Bus stations and stops in San Francisco, CA
San Francisco (5th/Townsend)
409 Townsend Street
San Francisco, CA 94107
United States
San Francisco, CA 94107
United States
View this address on Google Maps
Bus will board on the south side of the intersection of Townsend St and 5th St. The stop is located at a white curbside designated by a green FlixBus sign. Across the street is the "User Testing" building and several bike racks. Please stay clear of the green bike lane.
To view more info about this station, visit our page San Francisco (5th/Townsend)
San Francisco Bus Station
425 Mission St Ste 206
San Francisco, CA 94105
United States
San Francisco, CA 94105
United States
View this address on Google Maps
To view more info about this station, visit our page San Francisco Bus Station
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Frequently asked questions
Where are the Greyhound bus stops in San Francisco and in San Diego?
How long does the bus from San Francisco to San Diego take with Greyhound?
How much is the bus from San Francisco to San Diego and how can I buy a ticket?
How do I track my Greyhound bus from San Francisco to San Diego ?
How much baggage can I bring on the bus from San Francisco to San Diego?
Is traveling with Greyhound from San Francisco to San Diego environmentally-friendly?
What onboard services are available on Greyhound buses from San Francisco to San Diego?
What time is the first bus from San Francisco to San Diego?
What time is the last bus from San Francisco to San Diego?
Can I book bus tickets both for Greyhound and FlixBus to travel from San Francisco to San Diego?
How many daily Greyhound bus trips are there from San Francisco to San Diego?
What facilities does Greyhound provide for passengers with reduced mobility and service animals?
Plan your bus trip from San Francisco to San Diego with Greyhound
The trip from San Francisco to San Diego takes as short as 13 hours 5 minutes and could cost as little as $70.97. The first bus departs at 6:30 am and the last bus departs at 10:40 pm. Greyhound operates 3 bus rides daily between San Francisco and San Diego. When traveling with Greyhound to San Diego from San Francisco, expect free Wifi, power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to San Diego in seconds.How to Book Your Bus Ticket to San Diego from San Francisco
With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from San Francisco to San Diego, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to San Diego, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!Discover more popular bus connections
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Onboard services are subject to availability