Affordable bus tickets from Port St. Lucie, FL to Houston, TX

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Explore now

Enjoy free onboard entertainment

Watch a FREE movie and use our power outlets to stay powered up during your trip.

Find out what’s playing

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Window or Aisle?

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

Discover all your options

Bus stations and stops in Port St. Lucie, FL

Please note: your ticket will contain the most up-to-date address information.

Port St Lucie (Park & Ride)

2198 Sw Gatlin Blvd
Port St. Lucie, FL 34953
United States

View this address on Google Maps

To view more info about this station, visit our page Port St Lucie (Park & Ride)

Port St. Lucie

2031 SW Gatlin Blvd
Port St. Lucie, FL 34953
United States

View this address on Google Maps

Bus will board in the parking lot of the RaceTrac gas station on SW Gatlin Blvd. No long-term or overnight parking is allowed for FlixBus passengers.

To view more info about this station, visit our page Port St. Lucie

Bus stations and stops in Houston, TX

Please note: your ticket will contain the most up-to-date address information.

Houston Bus Station (Greyhound)

7000 Harrisburg Blvd
Houston, TX 77011
United States

Bus will board inside the Greyhound station. Passengers must present tickets to security prior to entering the back lobby where the bus loads. Passengers may ask staff for directions inside the terminal.

Effective 11/30/23 the bus stop will be moved to 7000 Harrisburg Blvd, Houston SE, TX 77011. This is the new location to use for purchasing tickets and bus stop.

View this address on Google Maps

To view more info about this station, visit our page Houston Bus Station (Greyhound)

Downtown Houston (Gray St.)

605 Gray St
Houston, TX 77002
United States

View this address on Google Maps

Bus will board in the parking lot at 605 Gray St. Wait for the bus at the East side of the parking lot closest to the intersection of Smith St. and Gray St. Please note: there is no parking available at this location.

To view more info about this station, visit our page Downtown Houston (Gray St.)

Houston Uptown/Upper Kirby

2525 Southwest Fwy
Houston, TX 77098
United States

View this address on Google Maps

Bus will board at the Timewise Food Store/Shell gas station lot. Board the bus at the northwest curb, adjacent to Kirby Dr and SW Freeway Service Rd.

To view more info about this station, visit our page Houston Uptown/Upper Kirby

The Woodlands

1201 Lake Woodlands Dr
Houston, TX 77380
United States

View this address on Google Maps

Bus will board in the striped loading zone adjacent to the Barnes and Noble and across from the parking garage. Please Note: Do not loiter or wait for the bus in the Pottery Barn AND do not park your car along the curb where the bus boards while waiting for the bus.

To view more info about this station, visit our page The Woodlands

Houston (Agencia Autobuses)

6590 Sw Freeway
Houston, TX 77074
United States

View this address on Google Maps

To view more info about this station, visit our page Houston (Agencia Autobuses)

North Houston

210 Patton Street
Houston, TX 77009
United States

View this address on Google Maps

Bus will board along the curb next to the grass directly below the Love's Travel Stop and Wendy's signs.

To view more info about this station, visit our page North Houston

Baytown (Thompson & I-10 Service Rd)

6800 Thompson Rd
Houston, TX 77521
United States

View this address on Google Maps

Bus will board inside the Shell station lot (TA Baytown Travel Center) on the front grassy curbside parallel to the I-10 Service Road in the northwest corner of the lot. /// Google Maps: https://goo.gl/maps/ZRS5wKahqfBs6nUo8 /// Coordinates: 29.79699, -95.031609

To view more info about this station, visit our page Baytown (Thompson & I-10 Service Rd)

Discover all the places you can go

Choose from almost 2,300 destinations with Greyhound, FlixBus and our connecting partners!

Port St. Lucie, FL - Houston, TX: Quick information

Online payment

Yes

Distance

926 miles

Direct connection

Yes

Environmentally-friendly travel?

Yes

Discover more popular bus connections

Onboard services are subject to availability