Affordable bus tickets from Mesa, AZ to San Diego, CA

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Explore now

Enjoy free onboard entertainment

Watch a FREE movie and use our power outlets to stay powered up during your trip.

Find out what’s playing

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Window or Aisle?

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

Discover all your options

Bus stations and stops in Mesa, AZ

Please note: your ticket will contain the most up-to-date address information.

Bus stations and stops in San Diego, CA

Please note: your ticket will contain the most up-to-date address information.

San Diego (Old Town-FlixBus)

2728 Congress St
San Diego, CA 92110
United States

View this address on Google Maps

Bus will board at the northbound white curb at the intersection of Congress St and Telegraph Way. Telegraph way is the dirt road entrance to “Old Town San Diego.” The loading curb is in front “State Park Lot B” and is indicated by a “No Parking” sign.

To view more info about this station, visit our page San Diego (Old Town-FlixBus)

San Diego Greyhound Bus Stop

4005 Taylor St
San Diego, CA 92110
United States

View this address on Google Maps

Bus will board at the southbound white curb on Congress St outside of the MTS Old Town Transit Center. The loading curb is along a black fence separating Congress St and the interior MTS bus boarding area.

To view more info about this station, visit our page San Diego Greyhound Bus Stop

San Diego (La Jolla - UC San Diego)

UCSD Health La Jolla Station
San Diego, CA 92093
United States

View this address on Google Maps

Bus will board in the southbound bus pullout zone on Campus Point Drive immediately south of the UC San Diego Health La Jolla Blue Line Trolley Station. Look for the ‘Passenger Loading Zone 43’ sign.

To view more info about this station, visit our page San Diego (La Jolla - UC San Diego)

San Diego (Downtown/Seaport Village)

789 W Harbor Dr
San Diego, CA 92101
United States

View this address on Google Maps

Bus will board at the curbside on W Harbor Dr adjacent to the “Headquarters at Seaport District” sign. Google Maps: https://goo.gl/maps/sTEy4a2ccMNyHMkv8

To view more info about this station, visit our page San Diego (Downtown/Seaport Village)

San Diego State University (Hardy Ave)

5716 Hardy Ave
San Diego, CA 92115
United States

View this address on Google Maps

Bus will board on the westbound curbside of Hardy Ave, west of the intersection at Campanile Dr and Hardy Ave. The stop is in front of Campanile Mall.

To view more info about this station, visit our page San Diego State University (Hardy Ave)

San Diego (Balboa Park)

Pan American Plaza and Presidents Way
San Diego, CA 92101
United States

View this address on Google Maps

Bus will board at the tour bus loading zone located on Presidents Way near Pan American Plaza at Balboa Park (SW part of the park). ***SPECIAL OFFER***: FlixBus riders who present their ticket will receive FREE admission to the San Diego Museum of Art at Balboa Park on the day of their trip.

To view more info about this station, visit our page San Diego (Balboa Park)

Discover all the places you can go

Choose from almost 2,300 destinations with Greyhound, FlixBus and our connecting partners!

Mesa, AZ - San Diego, CA: Quick information

Online payment

Yes

Distance

312 miles

Direct connection

Yes

Environmentally-friendly travel?

Yes

Discover more popular bus connections

Onboard services are subject to availability