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Bus from Key West, FL to Port St. Lucie, FL

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Bus stations and stops in Key West, FL

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Frequently asked questions

The first Greyhound bus from Key West to Port St. Lucie departs at 12:55 pm.
Onboard amenities on Greyhound buses from Key West to Port St. Lucie include free Wi-Fi, personal power outlets, reclining seats with extra legroom, overhead storage, and an onboard restroom.
Opting for Greyhound to travel from Key West to Port St. Lucie is an environmentally responsible choice, reducing traffic and lowering emissions compared to car travel.
When traveling from Key West to Port St. Lucie with Greyhound, you can bring one carry-on bag (up to 25 lbs, 16x12x7 inches) for free. Additionally, one checked bag is included, with a second bag free for Flexible fare passengers. Extra or oversized baggage can be added during booking or later through the "Manage My Booking" section. Some locations also allow in-person payment for additional luggage. Full details are available on our baggage policy page.
To track your bus from Key West to Port St. Lucie, use Greyhound’s bus tracker. This tool provides live updates on the bus’s location and expected arrival times.
Bus tickets from Key West to Port St. Lucie start at $37.99. For the best rates, it is recommended to book in advance via our app or website. You can pay online using debit or credit cards, or choose to pay in person with cash at selected locations.
The journey by Greyhound bus from Key West to Port St. Lucie covers approximately 296 miles. The quickest trip duration is 8 hours 35 minutes, .
The last Greyhound bus from Key West to Port St. Lucie leaves at 5:00 pm.
You can find the Greyhound bus stops in both Key West and Port St. Lucie by checking the map on this page, which shows the addresses and locations of all stops.
Greyhound buses are equipped with wheelchair lifts and have space for two passengers using wheelchairs or mobility scooters. We recommend booking your trip from Key West to Port St. Lucie in advance to secure the necessary accommodations. Service animals are also welcome on all Greyhound buses. For more details, visit our accessibility page.
Greyhound operates up to 1 trip daily from Key West to Port St. Lucie. You can find the schedule by entering your departure date in the search box above.
Yes, you can book both Greyhound and FlixBus tickets for travel from Key West to Port St. Lucie through our website. After selecting your cities and travel dates, you can compare the schedules and prices of both services.

Planning Your Greyhound Bus Trip from Key West to Port St. Lucie?

The journey from Key West to Port St. Lucie can take as little as 8 hours 35 minutes and starts from as little as $37.99. The earliest bus leaves at 12:55 pm and the last bus leaves at 5:00 pm. Greyhound provides daily buses Key West to Port St. Lucie from Key West to Port St. Lucie. Travel with Greyhound and enjoy complimentary Wifi, access to power sockets, and a comfortable seat throughout your trip. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Port St. Lucie in seconds.

How to Book Your Bus Ticket to Port St. Lucie from Key West

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Key West to Port St. Lucie, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Port St. Lucie, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability