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Bus from Columbia, SC to Sioux Falls, SD
More travel options
You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.
Enjoy free onboard Wi-Fi
We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.
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Bus stations and stops in Columbia, SC
Discover more popular bus connections
- Columbia, SC - Atlanta, GA
- Charlotte, NC - Columbia, SC
- Atlanta, GA - Columbia, SC
- Columbia, SC - Charlotte, NC
- North Charleston, SC - Columbia, SC
- Columbia, SC - North Charleston, SC
- Myrtle Beach, SC - Columbia, SC
- Columbia, SC - Myrtle Beach, SC
- Savannah, GA - Columbia, SC
- Florence, SC - Columbia, SC
- Columbia, SC - Washington, D.C.
- Columbia, SC - New York, NY
- Raleigh, NC - Columbia, SC
- Orangeburg, SC - Columbia, SC
- Columbia, SC - Savannah, GA
- Columbia, SC - Florence, SC
- Greensboro, NC - Columbia, SC
- Greenville, SC - Columbia, SC
- Birmingham, AL - Columbia, SC
- Fayetteville, NC - Columbia, SC
- Sioux Falls, SD - Minneapolis, MN
- Rapid City, SD - Sioux Falls, SD
- Minneapolis, MN - Sioux Falls, SD
- Sioux Falls, SD - Rapid City, SD
- Omaha, NE - Sioux Falls, SD
- Sioux Falls, SD - Omaha, NE
- Fargo, ND - Sioux Falls, SD
- Sioux Falls, SD - Fargo, ND
- Atlanta, GA - Sioux Falls, SD
- Kansas City, MO - Sioux Falls, SD
- Sioux Falls, SD - Sioux City, IA
- Sioux Falls, SD - St. Paul, MN
- Sioux Falls, SD - Mitchell, SD
- Sioux Falls, SD - Chicago, IL
- Sioux Falls, SD - New York, NY
- Bismarck, ND - Sioux Falls, SD
- Sioux Falls, SD - Huntsville, AL
- Chicago, IL - Sioux Falls, SD
- Vermillion, SD - Sioux Falls, SD
- Sioux Falls, SD - Albert Lea, MN
Onboard services are subject to availability