Bus from Columbia, MO to Panama City, FL

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

What to expect of your trip

Fast, easy, and affordable options from Columbia, MO to Panama City, FL

Avg. trip duration

30hr51mins

Avg. distance

1260 miles

Cheapest trip

From $121.94

3

Avg. trips a day

Safe Payment

Use Paypal, Google Pay, Visa & International cards

Easy to buy

Get your tickets online, in our App, or in a Flixshop

Customer care

Effortless support from booking to travel

Bus stations and stops in Columbia, MO

Please note: your ticket will contain the most up-to-date address information.

Columbia (Midway Travel Plaza)

6401 Hwy 40 West
Columbia, MO 65202
United States

View this address on Google Maps

The bus will stop at the Midway Travel Plaza off of I-40 and I-70.

To view more info about this station, visit our page Columbia (Midway Travel Plaza)

Columbia (Wabash Station)

126 N 10Th St
Columbia, MO 65201
United States

View this address on Google Maps

The bus will stop at the Wabash Bus Station off of N 10th St and Artist Aly. On SUNDAYS ONLY, the bus will stop on the south side.

To view more info about this station, visit our page Columbia (Wabash Station)

Best service on board

Available options you can find for a more comfortable trip:

Free WiFi

Stay connected throughout your journey

Power Outlets

Keep your devices charged on the go

Comfortable seats

Relax with extra legroom and reclining seats

Luggage storage

Space to safely stow your belongings

Toilets

Conveniently available on every FlixBus

First time travelling with us?

Frequently asked questions

How much is the Columbia to Panama City bus and how can I buy a ticket?

The Columbia to Panama City bus starts from $121.94. Booking in advance, whether on the app or website, is the best way to get the most affordable bus travel. If you book online, you can choose to pay with a debit card or credit card on the Greyhound app or website. If you prefer, you can also pay in person with cash.

Can I book bus tickets both for Greyhound and FlixBus to travel from Columbia to Panama City?

Yes, on this website you can book both Greyhound and FlixBus tickets from Columbia to Panama City. You can check both the Greyhound and FlixBus ride schedules once you select your departure city, destination city, and desired trip date.

How long does the bus from Columbia to Panama City take with Greyhound?

The bus trip from Columbia to Panama City is about 1060 miles long. The quickest trip with Greyhound takes 25 hours 30 minutes.

How many daily Greyhound bus trips are there from Columbia to Panama City?

Greyhound runs up to 4 rides per day from Columbia to Panama City. You can search for your preferred departure date and check the schedule using the search bar above.

How do I track my Greyhound bus from Columbia to Panama City ?

You can track the status of your Columbia to Panama City bus using Greyhound's bus tracker. With this tool, you can see the real-time location of your bus and get updates on its departure and arrival times.

What onboard services are available on Greyhound buses from Columbia to Panama City?

Onboard services available on Greyhound buses from Columbia to Panama City include free Wi-Fi for all passengers, personal power outlets near every seat, reclining leather seats with footrests, extra legroom, overhead storage, and an on-board restroom.

What time is the first bus from Columbia to Panama City?

The first Greyhound bus to Panama City from Columbia leaves at 8:30 am.

What time is the last bus from Columbia to Panama City?

The last Greyhound bus to Panama City from Columbia leaves at 8:05 pm.

How much baggage can I bring on the bus from Columbia to Panama City?

When traveling on the bus from Columbia to Panama City with Greyhound, you can bring one carry-on bag with you (maximum 25 lbs, 16x12x7 inches). You can store one bag under the bus for free, and if you have a Flexible fare, the second bag stored under the bus is also free. You can also carry additional or bulky baggage for a supplementary charge. You can reserve extra baggage while booking your ticket on our website or app. Alternatively, you can add bulky items later through the 'Manage My Booking' section. If your departure is from a location with Greyhound personnel, you can book and pay for your extra luggage there. For more information, please refer to our baggage policy page here.

What facilities does Greyhound provide for passengers with reduced mobility and service animals?

Greyhound buses are equipped with wheelchair lifts to assist passengers using wheelchairs or mobility scooters. Each bus has space for two passengers with these devices. It's recommended to book your bus from Columbia to Panama City in advance to ensure a spot. If you'd like to transfer to a regular seat, our drivers will stow your device for you. Service animals are also welcome on board our buses. For further details on accessibility and service animal policies, please check this link.

Is traveling with Greyhound from Columbia to Panama City environmentally-friendly?

Traveling by bus from Columbia to Panama City with Greyhound is a convenient and environmentally responsible choice, as bus travel reduces traffic and emissions compared to traveling by car.

Where are the Greyhound bus stops in Columbia and in Panama City?

You can easily find the locations and addresses of the bus stops in Columbia and in Panama City on this page: check the address and their location on the map!

Columbia has 2 bus stop(s), namely: Columbia (Midway Travel Plaza), Columbia (Wabash Station)
Panama City has 1 bus stop(s), namely: Panama City Beach Bus Station

Plan your bus trip from Columbia to Panama City with Greyhound

The trip from Columbia to Panama City takes as short as 25 hours 30 minutes and could cost as little as $121.94. The first bus departs at 8:30 am and the last bus departs at 8:05 pm. Greyhound operates 4 bus rides daily between Columbia and Panama City. When traveling with Greyhound to Panama City from Columbia, expect free Wifi, power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Panama City in seconds.

How to Book Your Bus Ticket to Panama City from Columbia

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Columbia to Panama City, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Panama City, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

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Onboard services are subject to availability