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Bus from Watertown, SD to Des Moines, IA

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More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

Bus stations and stops in Watertown, SD

Please note: your ticket will contain the most up-to-date address information.

Onboard services are subject to availability