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Bus from Orangeburg, SC to Winston-Salem, NC

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Bus stations and stops in Orangeburg, SC

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Frequently asked questions

The travel time from Orangeburg to Winston-Salem by bus is approximately 8 hours 30 minutes, covering a distance of about 222 miles. The fastest route includes .
You can check the status of your Greyhound bus traveling from Orangeburg to Winston-Salem by using our bus tracker. This tool provides real-time updates on your bus’s location and expected arrival time.
For your trip from Orangeburg to Winston-Salem, Greyhound allows one carry-on bag (max 25 lbs, 16x12x7 inches) and one checked bag under the bus at no extra charge. A second checked bag is free with a Flexible fare. You can add extra baggage during booking or later via "Manage My Booking," or at certain locations. Full details are on our baggage policy page.
Traveling by Greyhound from Orangeburg to Winston-Salem is an environmentally friendly option, helping to reduce carbon emissions and traffic congestion compared to car travel.
On Greyhound buses from Orangeburg to Winston-Salem, you can enjoy free Wi-Fi, power outlets at each seat, comfortable reclining seats with extra legroom, overhead storage, and access to an onboard restroom.
The earliest bus from Orangeburg to Winston-Salem departs at 1:40 pm.
The latest bus from Orangeburg to Winston-Salem leaves at 10:30 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Orangeburg to Winston-Salem on our website. Simply enter your travel details to compare schedules and fares.
There are up to 2 Greyhound buses operating daily from Orangeburg to Winston-Salem. Check the schedule by entering your travel date in the search box above.
Greyhound offers wheelchair lifts and space for passengers using mobility devices. It is recommended to book your trip from Orangeburg to Winston-Salem in advance. Service animals are welcome on all Greyhound buses. For more information, visit our accessibility page.
The locations of Greyhound bus stops in Orangeburg and Winston-Salem can be found on this page, along with detailed maps and addresses.

Planning Your Greyhound Bus Trip from Orangeburg to Winston-Salem?

How to Book Your Bus Ticket to Winston-Salem from Orangeburg

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Orangeburg to Winston-Salem, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Winston-Salem, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability