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Bus from Harrisburg, PA to Lake City, FL

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Bus stations and stops in Harrisburg, PA

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Frequently asked questions

The first Greyhound bus from Harrisburg to Lake City departs at 3:05 am.
Onboard amenities on Greyhound buses from Harrisburg to Lake City include free Wi-Fi, personal power outlets, reclining seats with extra legroom, overhead storage, and an onboard restroom.
Opting for Greyhound to travel from Harrisburg to Lake City is an environmentally responsible choice, reducing traffic and lowering emissions compared to car travel.
When traveling from Harrisburg to Lake City with Greyhound, you can bring one carry-on bag (up to 25 lbs, 16x12x7 inches) for free. Additionally, one checked bag is included, with a second bag free for Flexible fare passengers. Extra or oversized baggage can be added during booking or later through the "Manage My Booking" section. Some locations also allow in-person payment for additional luggage. Full details are available on our baggage policy page.
To track your bus from Harrisburg to Lake City, use Greyhound’s bus tracker. This tool provides live updates on the bus’s location and expected arrival times.
The journey by Greyhound bus from Harrisburg to Lake City covers approximately 1196 miles. The quickest trip duration is 28 hours 5 minutes, .
The last Greyhound bus from Harrisburg to Lake City leaves at 9:05 pm.
You can find the Greyhound bus stops in both Harrisburg and Lake City by checking the map on this page, which shows the addresses and locations of all stops.
Greyhound buses are equipped with wheelchair lifts and have space for two passengers using wheelchairs or mobility scooters. We recommend booking your trip from Harrisburg to Lake City in advance to secure the necessary accommodations. Service animals are also welcome on all Greyhound buses. For more details, visit our accessibility page.
Greyhound operates up to 1 trip daily from Harrisburg to Lake City. You can find the schedule by entering your departure date in the search box above.
Yes, you can book both Greyhound and FlixBus tickets for travel from Harrisburg to Lake City through our website. After selecting your cities and travel dates, you can compare the schedules and prices of both services.

Plan your bus trip from Harrisburg to Lake City with Greyhound

The first bus departs at 3:05 am and the last bus departs at 9:05 pm. Greyhound offers daily bus rides from Harrisburg to Lake City. When traveling with Greyhound to Lake City from Harrisburg, expect free Wifi, power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Lake City in seconds.

How to Book Your Bus Ticket to Lake City from Harrisburg

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Harrisburg to Lake City, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Lake City, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability