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Bus from Gainesville, FL to North Charleston, SC

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Bus stations and stops in Gainesville, FL

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Frequently asked questions

The first Greyhound bus from Gainesville to North Charleston departs at 1:00 am.
Onboard amenities on Greyhound buses from Gainesville to North Charleston include free Wi-Fi, personal power outlets, reclining seats with extra legroom, overhead storage, and an onboard restroom.
Opting for Greyhound to travel from Gainesville to North Charleston is an environmentally responsible choice, reducing traffic and lowering emissions compared to car travel.
When traveling from Gainesville to North Charleston with Greyhound, you can bring one carry-on bag (up to 25 lbs, 16x12x7 inches) for free. Additionally, one checked bag is included, with a second bag free for Flexible fare passengers. Extra or oversized baggage can be added during booking or later through the "Manage My Booking" section. Some locations also allow in-person payment for additional luggage. Full details are available on our baggage policy page.
To track your bus from Gainesville to North Charleston, use Greyhound’s bus tracker. This tool provides live updates on the bus’s location and expected arrival times.
Bus tickets from Gainesville to North Charleston start at $86.99. For the best rates, it is recommended to book in advance via our app or website. You can pay online using debit or credit cards, or choose to pay in person with cash at selected locations.
The journey by Greyhound bus from Gainesville to North Charleston covers approximately 508 miles. The quickest trip duration is 15 hours 10 minutes, .
The last Greyhound bus from Gainesville to North Charleston leaves at 10:40 pm.
You can find the Greyhound bus stops in both Gainesville and North Charleston by checking the map on this page, which shows the addresses and locations of all stops.
Greyhound buses are equipped with wheelchair lifts and have space for two passengers using wheelchairs or mobility scooters. We recommend booking your trip from Gainesville to North Charleston in advance to secure the necessary accommodations. Service animals are also welcome on all Greyhound buses. For more details, visit our accessibility page.
Greyhound operates up to 1 trip daily from Gainesville to North Charleston. You can find the schedule by entering your departure date in the search box above.
Yes, you can book both Greyhound and FlixBus tickets for travel from Gainesville to North Charleston through our website. After selecting your cities and travel dates, you can compare the schedules and prices of both services.

Plan your bus trip from Gainesville to North Charleston with Greyhound

The trip from Gainesville to North Charleston takes as short as 15 hours 10 minutes and could cost as little as $86.99. The first bus departs at 1:00 am and the last bus departs at 10:40 pm. Greyhound offers daily bus rides from Gainesville to North Charleston. When traveling with Greyhound to North Charleston from Gainesville, expect free Wifi, power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to North Charleston in seconds.

How to Book Your Bus Ticket to North Charleston from Gainesville

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Gainesville to North Charleston, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to North Charleston, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability