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Bus from Detroit, MI to Louisville, KY

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More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

On this page

Bus stations and stops in Detroit, MI

Please note: your ticket will contain the most up-to-date address information.

Discover all the places you can go

Choose from almost 2,300 destinations with Greyhound, FlixBus and our connecting partners!

Frequently asked questions

The Detroit to Louisville bus starts from $55.98. Booking in advance, whether on the app or website, is the best way to get the most affordable bus travel. If you book online, you can choose to pay with a debit card or credit card on the Greyhound app or website. If you prefer, you can also pay in person with cash.
Yes, on this website you can book both Greyhound and FlixBus tickets from Detroit to Louisville. You can check both the Greyhound and FlixBus ride schedules once you select your departure city, destination city, and desired trip date.
The bus trip from Detroit to Louisville is about 373 miles long. The quickest trip with Greyhound takes 7 hours 25 minutes.
You can track the status of your Detroit to Louisville bus using Greyhound's bus tracker. With this tool, you can see the real-time location of your bus and get updates on its departure and arrival times.
Greyhound runs up to 3 rides per day from Detroit to Louisville. You can search for your preferred departure date and check the schedule using the search bar above.
Onboard services available on Greyhound buses from Detroit to Louisville include free Wi-Fi for all passengers, personal power outlets near every seat, reclining leather seats with footrests, extra legroom, overhead storage, and an on-board restroom.
The first Greyhound bus to Louisville from Detroit leaves at 6:40 am.
The last Greyhound bus to Louisville from Detroit leaves at 11:25 pm.
When traveling on the bus from Detroit to Louisville with Greyhound, you can bring one carry-on bag with you (maximum 25 lbs, 16x12x7 inches). You can store one bag under the bus for free, and if you have a Flexible fare, the second bag stored under the bus is also free. You can also carry additional or bulky baggage for a supplementary charge. You can reserve extra baggage while booking your ticket on our website or app. Alternatively, you can add bulky items later through the 'Manage My Booking' section. If your departure is from a location with Greyhound personnel, you can book and pay for your extra luggage there. For more information, please refer to our baggage policy page here.
You can easily find the locations and addresses of the bus stops in Detroit and in Louisville on this page: check the address and their location on the map!
  • Detroit has 1 bus stop(s), namely: Detroit Bus Station
  • Louisville has 1 bus stop(s), namely: Louisville Bus Station
Traveling by bus from Detroit to Louisville with Greyhound is a convenient and environmentally responsible choice, as bus travel reduces traffic and emissions compared to traveling by car.
Greyhound buses are equipped with wheelchair lifts to assist passengers using wheelchairs or mobility scooters. Each bus has space for two passengers with these devices. It's recommended to book your bus from Detroit to Louisville in advance to ensure a spot. If you'd like to transfer to a regular seat, our drivers will stow your device for you. Service animals are also welcome on board our buses. For further details on accessibility and service animal policies, please check this link.

Onboard services are subject to availability