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Bus from Mesquite, NV to Upton, KY

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

What to expect of your trip

Fast, easy, and affordable options from Mesquite, NV to Upton, KY

On this page

Bus stations and stops in Mesquite, NV

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
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Free WiFi
Stay connected throughout your journey
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Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Frequently asked questions

The travel time from Mesquite to Upton by bus is approximately 49 hours 50 minutes, covering a distance of about 2149 miles.
You can check the status of your Greyhound bus traveling from Mesquite to Upton by using our bus tracker. This tool provides real-time updates on your bus’s location and expected arrival time.
For your trip from Mesquite to Upton, Greyhound allows one carry-on bag (max 25 lbs, 16x12x7 inches) and one checked bag under the bus at no extra charge. A second checked bag is free with a Flexible fare. You can add extra baggage during booking or later via "Manage My Booking," or at certain locations. Full details are on our baggage policy page.
Traveling by Greyhound from Mesquite to Upton is an environmentally friendly option, helping to reduce carbon emissions and traffic congestion compared to car travel.
On Greyhound buses from Mesquite to Upton, you can enjoy free Wi-Fi, power outlets at each seat, comfortable reclining seats with extra legroom, overhead storage, and access to an onboard restroom.
The earliest bus from Mesquite to Upton departs at 10:05 pm.
The latest bus from Mesquite to Upton leaves at 10:05 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Mesquite to Upton on our website. Simply enter your travel details to compare schedules and fares.
There are up to one Greyhound bus operating daily from Mesquite to Upton. Check the schedule by entering your travel date in the search box above.
Greyhound offers wheelchair lifts and space for passengers using mobility devices. It is recommended to book your trip from Mesquite to Upton in advance. Service animals are welcome on all Greyhound buses. For more information, visit our accessibility page.
The locations of Greyhound bus stops in Mesquite and Upton can be found on this page, along with detailed maps and addresses.

Planning Your Greyhound Bus Trip from Mesquite to Upton?

How to Book Your Bus Ticket to Upton from Mesquite

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Mesquite to Upton, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Upton, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability